SVM-BPfinder

SVM-BPfinder: a tool for mammalian U2 branch point prediction developed by the Computational RNA Biology Group. The branch point (BP) is one of the three obligatory signals required for pre-mRNA splicing. In mammals, the degeneracy of the motif combined with the lack of a large set of experimentally verified BPs complicates the task of modeling it in silico, and therefore of predicting the location of natural BPs. Consequently, BPs have been disregarded in a considerable fraction of the genome-wide studies on the regulation of splicing in mammals. SVM-BPfinder allows the right prediction of BPs.